abstract：:Autoantibodies directed against nucleic acid and protein complexes present in cell nuclei characterize autoimmune diseases and are employed in diagnosis. The mechanisms by which these autoantigens escape immunological tolerance are largely unknown, but a number of recent observations suggest that modified self-protein...

journal_title：Archives of oral biology

authors： McArthur C,Wang Y,Veno P,Zhang J,Fiorella R

更新日期：2002-06-01 00:00:00

abstract：:Masticatory muscle electromyograms (EMGs) were recorded while patients with bulbar myasthenia gravis chewed artificial food and compared with those of patients with ocular myasthenia gravis, patients in clinical remission who had previously suffered from bulbar myasthenia gravis and healthy individuals. Masticatory pe...

journal_title：Archives of oral biology

authors： Weijnen FG,van der Bilt A,Kuks JB,van der Glas HW,Oudenaarde I,Bosman F

更新日期：2002-05-01 00:00:00

abstract：:Recent studies of the manipulation and reduction of food in the human mouth have used lateral-projection videofluorography (VFG) and so have concerned antero-posterior food movement. To determine the degree to which (a) food was chewed bilaterally as opposed to unilaterally, (b) the frequency of side changes, (c) the ...

journal_title：Archives of oral biology

authors： Mioche L,Hiiemae KM,Palmer JB

更新日期：2002-04-01 00:00:00

abstract：:The role of oxygen in the regulation of the pulpal microcirculation is unknown. This investigation is aimed to measure tissue oxygen tension and blood-flow changes in the pulp of rat lower incisors during graded systemic hyperoxia, and to determine the response of the pulpal vasculature to various oxygen tensions. Twe...

journal_title：Archives of oral biology

authors： Yu CY,Boyd NM,Cringle SJ,Alder VA,Yu DY

更新日期：2002-03-01 00:00:00

abstract：:The retrognathic Brachyrrhine (Br) heterozygote mouse mutant has a very localized morphological deficiency in the sphenoethmoidal region of the anterior cranial base. The purpose of this study was to test the hypothesis that a primary growth defect occurs in that region of Br mice. Primary cell cultures were derived f...

journal_title：Archives of oral biology

authors： Ma W,Lozanoff S

更新日期：2002-02-01 00:00:00

abstract：:The permeability characteristics of dentine have been used in many in vitro studies to evaluate longitudinally the efficacy of various restorative and preventative procedures. However, the permeability of human dentine increases over time after tooth extraction. The aim here was to determine if there is a steady phase...

journal_title：Archives of oral biology

authors： Ozok AR,Wu MK,Wesselink PR

更新日期：2002-01-01 00:00:00

abstract：:The bioconcentration of lipophilic organochlorines in ovine dentine in comparison to adipose tissue was examined. Sheep were given a single dose (0.2-1.4 mg/kg body wt) of individual polychlorobiphenyl (PCB) congeners (tetrachlorobiphenyls IUPAC Nos. 54 and 80, and hexachlorobiphenyls IUPAC Nos. 155 and 169) and organ...

journal_title：Archives of oral biology

authors： Jan J,Vrecl M,Pogacnik A,Gaspersic D

更新日期：2001-12-01 00:00:00

abstract：:The forces that develop in the human temporomandibular joint during function have never been directly measured, yet many patients exhibit excessive localized wear and tear of the joint, suggesting that at times these forces exceed tissue tolerance. The purpose here was to gain insight into vibration transmission betwe...

journal_title：Archives of oral biology

authors： Hashimoto K,Clark GT

更新日期：2001-11-01 00:00:00

abstract：:The soluble N-ethylmaleimide-sensitive fusion (NSF) attachment protein (SNAP) receptor (SNARE) hypothesis has been applied to exocytosis in salivary glands. The expression of SNARE proteins has not been well investigated in the parotid gland. In this study, the mRNA expression of SNAREs and membrane-fusion-related pro...

journal_title：Archives of oral biology

authors： Imai A,Nashida T,Shimomura H

更新日期：2001-10-01 00:00:00

abstract：:The purpose was to examine the effect of brief intrusive forces on human pulpal blood flow (PBF). Laser Doppler flowmetric measurements were made from 17 vital upper left central incisors of 17 participants who had clinically healthy tooth crowns and periodontal tissues. Brief intrusive forces (0.5,1,5 N; duration 20 ...

journal_title：Archives of oral biology

authors： Ikawa M,Fujiwara M,Horiuchi H,Shimauchi H

更新日期：2001-09-01 00:00:00

abstract：:One dentine specimen was prepared from each of 90 bovine incisors. The samples were then evenly distributed among nine groups (A-I) and submitted to 10 alternating de- and re-mineralization cycles, including abrasion by tooth brushing. Each cycle started with a demineralization using the erosive soft drink Sprite Ligh...

journal_title：Archives of oral biology

authors： Attin T,Buchalla W,Putz B

更新日期：2001-09-01 00:00:00

abstract：:Chronic graft-versus-host disease (cGVHD) is a complex clinical entity with various target organs, including the salivary glands. Oral pilocarpine (Salagen(R)), 30 mg/day, can ameliorate cGVHD-induced xerostomia and improve the flow rate from the major salivary glands. The purpose here was to evaluate the effect of th...

journal_title：Archives of oral biology

authors： Nagler RM,Nagler A

更新日期：2001-08-01 00:00:00

abstract：:Apoptosis in regressive primary (deciduous) dental primordia was examined in the embryos of Suncus murinus, which is a monophyodont. The primary tooth germs of S. murinus are temporarily formed and disappear during the embryonic period before they are calcified. Most primary tooth germs reach the bell stage and degene...

journal_title：Archives of oral biology

authors： Sasaki C,Sato T,Kozawa Y

更新日期：2001-07-01 00:00:00

abstract：:The change in expression of MUC1 from health to disease forms the basis of its use as a potential disease marker. Previous attempts at isolating MUC1 from normal, healthy human oral mucosa have, however, drawn conflicting conclusions as to its presence. Furthermore, when MUC1 was detected in the oral glycocalyx, it wa...

journal_title：Archives of oral biology

authors： Sengupta A,Valdramidou D,Huntley S,Hicks SJ,Carrington SD,Corfield AP

更新日期：2001-06-01 00:00:00

abstract：:A recent preliminary (unpublished) study showed that phosphodiesterase (PDE) 3A and 3B are expressed in rat submandibular glands. Here, PDE3 activity was detected in homogenates of rat submandibular gland acinar epithelial (SMIE) cells, but not rat A5 (epithelial duct) cells. Most of the PDE3 activity in SMIE cells wa...

journal_title：Archives of oral biology

authors： Murata T,Sugatani T,Manganiello VC,Shimizu K,Tagawa T

更新日期：2001-05-01 00:00:00

abstract：:Stimulation of muscarinic cholinergic receptors on rat parotid acinar cells causes a rapid production of inositol phosphates, with the key metabolic event being the breakdown of phosphatidylinositol 4,5-bisphosphate into inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and diacylglycerol. Here a high-performance liquid chr...

journal_title：Archives of oral biology

authors： Tritsaris K,Gromada J,Jørgensen TD,Nauntofte B,Dissing S

更新日期：2001-04-01 00:00:00

abstract：:A common finding in Swedish children is hypomineralization in first molars of unknown cause. Little is known about the chemical composition of the disturbed enamel. The aim here was to analyse the concentration gradients for F, Cl, Na, Mg, K and Sr in hypomineralized enamel from 17 permanent molars by means of seconda...

journal_title：Archives of oral biology

authors： Jälevik B,Odelius H,Dietz W,Norén J

更新日期：2001-03-01 00:00:00

abstract：:A microtitre assay has been developed using hydroxyapatite-coated wells and Streptococcus sanguis NCTC 10904 at 10(7) cells per ml. A number of models representing toothpaste and mouthwash usage were adopted to detect the anti-adherent efficacy of a polyvinylmethylether maleic acid copolymer (PVM/MA), polyoxypropylene...

journal_title：Archives of oral biology

authors： Guan YH,de Graaf T,Lath DL,Humphreys SM,Marlow I,Brook AH

更新日期：2001-02-01 00:00:00

abstract：:Masticatory efficiency depends upon the ability of the molar cusps to apply concentrated bite forces to food particles and simultaneously to withstand the dental stresses that may cause enamel fracture. This study investigated how low-crowned molar cusps in omnivorous mammals, specifically humans, Homo sapiens, and pi...

journal_title：Archives of oral biology

authors： Popowics TE,Rensberger JM,Herring SW

更新日期：2001-01-01 00:00:00

abstract：:The expression and distribution of inducible nitric oxide synthase (iNOS) was examined in 12 samples of human temporomandibular joint (TMJ) with internal derangement (ID) and four control specimens. In the diseased joints, strong or definite iNOS reactivity was expressed in synovial lining and endothelial cells; weake...

journal_title：Archives of oral biology

authors： Homma H,Takahashi T,Seki H,Ohtani M,Kondoh T,Fukuda M

更新日期：2001-01-01 00:00:00

abstract：:Many studies have shown that various myosin isoforms are involved in muscle contraction. A search for specific antibodies directed against the myosin heavy chain (MHC) resulted in the identification of at least two main classes, referred to as MHC type I and type II. In this study, immunohistology and gel electrophore...

journal_title：Archives of oral biology

authors： Muller J,Vayssiere N,Muller A,Marti-Mestres G,Mornet D

更新日期：2000-12-01 00:00:00

abstract：:Fluorescence polarization (FP) was examined as a rapid quantitative method to assay the proteases in subgingival plaque. Protease activity was measured by a decrease in FP at 0.5-min intervals over 5 min, using BODIPY-alpha-casein, a protein substrate. To quantitate activity, the least absolute deviation (LAD) slope f...

journal_title：Archives of oral biology

authors： Grys EL,Schade SZ,Cohen ME,Geivelis M,Robinson PJ,Simonson LG

更新日期：2000-12-01 00:00:00

abstract：:Twenty-nine parotids ligated for between 1 and 365 days were examined by light and electron microscopy. Major changes in the acini were seen at 4 days and included vacuolation, disintegration, extravasation, apoptosis, phagy and a reduction in number and size of secretory granules. There was a further reduction in sec...

journal_title：Archives of oral biology

authors： Harrison JD,Fouad HM,Garrett JR

更新日期：2000-11-01 00:00:00

abstract：:It is well accepted that reduced masticatory function induced by a diet with soft physical consistency causes alterations in the craniofacial morphology in growing animals. It is assumed that these alterations are associated with reduced proliferative activity of osteoblasts on the bone surface, indicating a significa...

journal_title：Archives of oral biology

authors： Tokimasa C,Kawata T,Fujita T,Kaku M,Kawasoko S,Kohno S,Tanne K

更新日期：2000-10-01 00:00:00

abstract：:Non-invasive magnetic stimulation of the brain was earlier used to reveal the corticomotor representation of the human masseter muscle but it is unclear how motor tasks affect this map. An experimental approach incorporating transcranial magnetic stimulation of verified locations on the scalp, surface electromyography...

journal_title：Archives of oral biology

authors： Watson C,Walshaw D,McMillan AS

更新日期：2000-09-01 00:00:00

abstract：:To evaluate the role played by androgens in the development and maintenance of sex differences in the proportion of muscle fibres of different phenotypes, the effects of castration in adult (>6 months old) and in young adult (2-3 months old) male rabbits was examined. Immunohistochemical methods were used to evaluate ...

journal_title：Archives of oral biology

authors： Eason JM,Schwartz G,Shirley KA,English AW

更新日期：2000-08-01 00:00:00

abstract：:Casein phosphopeptides (CPP) stabilize amorphous calcium phosphate (ACP) and may be used to localize ACP in dental plaque, maintaining a state of supersaturation with respect to tooth enamel, reducing demineralization and enhancing remineralization. The aim here was to investigate these effects by measuring the effect...

journal_title：Archives of oral biology

authors： Rose RK

更新日期：2000-07-01 00:00:00

abstract：:Normal function of the lateral pterygoid muscle is not well understood. The principal aim of this study was to determine whether there is a progressive decrease in lateral pterygoid activity as the condyle moves posteriorly and superiorly during the return phase of a contralateral or protrusive jaw movement, as would ...

journal_title：Archives of oral biology

authors： Phanachet I,Murray GM

更新日期：2000-06-01 00:00:00

abstract：:The dental pulp is richly innervated by peptidergic nociceptive neurones that are of special interest because of their central role in dental pain and because they have some features that are not typical of other somatic nociceptors. Here, (35)S-riboprobes were used to determine whether pulpal afferents of adult (2-mo...

journal_title：Archives of oral biology

authors： Pan M,Naftel JP,Wheeler EF

更新日期：2000-05-01 00:00:00

abstract：:Although the formation of biofilms has been much studied, detachment of adherent cells from biofilms has been relatively neglected. Recent results have shown that adherent Streptococcus mutans cells can actively detach from epon-hydroxylapatite (EHA) rods conditioned with hog gastric mucin. The mechanisms for adherenc...

journal_title：Archives of oral biology

authors： Vats N,Lee SF

更新日期：2000-04-01 00:00:00

abstract：:Bone morphogenetic protein-7 (BMP-7) affects differentiation of preosteoblasts enabling the resultant cells to respond optimally to acutely acting regulators. As the phosphoinositide cascade and, particularly, the calcium-mobilizing inositol 1,4,5-trisphosphate (InsP3) receptor are integral to stimulus-secretion coupl...

journal_title：Archives of oral biology

authors： Bradford PG,Maglich JM,Ponticelli AS,Kirkwood KL

更新日期：2000-02-01 00:00:00

abstract：:The aim was to establish defined-species consortium plaque biofilms to investigate enamel and root caries in an artificial mouth. Strains of the putative enamel and root caries pathogens, Streptococcus mutans, Strep. sobrinus, Actinomyces naeslundii and Lactobacillus rhamnosus, were screened in batch culture for poten...

journal_title：Archives of oral biology

authors： Shu M,Wong L,Miller JH,Sissons CH

更新日期：2000-01-01 00:00:00

abstract：:The present study was designed to investigate the mechanical properties and load-relaxation of these discs in compression. Eight discs were used for the experiments. Compression was applied to specimens up to the specified strain, and a series of load-relaxation tests was conducted on each specimen from 0.25% strain t...

journal_title：Archives of oral biology

authors： Tanaka E,Tanaka M,Miyawaki Y,Tanne K

更新日期：1999-12-01 00:00:00

abstract：:The abrasiveness of food is a key determinant in the rate of physiological attrition (dental wear) in humans. With increasing food processing through time, the rate of physiological dental wear in human teeth has decreased markedly. Many consider such wear to be beneficial to oral health and that insufficient wear may...

journal_title：Archives of oral biology

authors： Sengupta A,Whittaker DK,Barber G,Rogers J,Musgrave JH

更新日期：1999-11-01 00:00:00

abstract：:The purpose was to investigate the relation between fluoride concentrations in whole saliva, parotid ductal saliva, and plasma in 5- to 10-year-old children (n = 17). Two stimulated whole-saliva samples were obtained from each child. Before the second sample was obtained, each child rinsed several times with a total o...

journal_title：Archives of oral biology

authors： Whitford GM,Thomas JE,Adair SM

更新日期：1999-10-01 00:00:00

abstract：:The characteristics of the mucosal immune response to Streptococcus mutans cells, antigen A, antigen B, glucosyltransferases and glucan-binding proteins were examined in four pregnant chimpanzees that had been immunized perorally with Strep. mutans. Six pregnant chimpanzees served as non-immunized controls. None of th...

journal_title：Archives of oral biology

authors： Tyler BM,Cole MF

更新日期：1999-10-01 00:00:00

abstract：:Dental follicle has been implicated as the origin of alveolar bone, cementum and periodontal ligament, but there is no direct evidence of their cellular lineage. The present pilot study was designed to characterize the phenotype of cultured cells obtained from the dental follicle of neonatal mouse molars. Developing m...

journal_title：Archives of oral biology

authors： Hou LT,Liu CM,Chen YJ,Wong MY,Chen KC,Chen J,Thomas HF

更新日期：1999-09-01 00:00:00

abstract：:The distribution of substance P (SP)-containing synaptic terminals in the hypoglossal nucleus (XII) of adult rats was examined by retrograde peroxidase labelling and immunocytochemistry. From the location of peroxidase injections into the tongue and of labelled neurones in the ventral lamina of XII, motor neurones tha...

journal_title：Archives of oral biology

authors： Hinrichsen CF,Weston S

更新日期：1999-08-01 00:00:00

abstract：:Although it is well known that somatostatin (SRIF) modulates several digestive functions, there are only a few reports about its effect on the salivary glands. Here, the action of SRIF parotid secretion was studied, in vivo and in vitro, in male Wistar rats. In vivo SRIF infusion (35 microg/kg per hr) inhibited the pa...

journal_title：Archives of oral biology

authors： Ostuni MA,Raimondi AR,Tumilasci OR

更新日期：1999-07-01 00:00:00

abstract：:Fluorescently labelled latex microspheres (0.01, 0.1 and 1.0 micron dia.) were used to establish whether oral epithelial cells could exhibit an endocytic function. Oral mucosa biopsies were incubated in organ culture at 37 degrees C for 20 h with one of the three sizes of fluorescent microspheres in the medium. Tissue...

journal_title：Archives of oral biology

authors： Innes NP,Ogden GR

更新日期：1999-06-01 00:00:00